interleukin 22 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T76775	Fezakinumab	ILV 094	Interleukin
	Fezakinumab is a potent monoclonal antibody to interleukin-22 (IL-22). Fezakinumab can be used to study immune system diseases and inflammation-related conditions such as psoriasis, rheumatoid arthritis and atopic dermat...
T1955	SB225002		CXCR
	SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.
T76803	Elsilimomab
	Elsilimomab (B-E8), an IgG1 monoclonal antibody targeting interleukin-6 (IL-6), exhibits a dissociation constant (K D) of 22 pM and an inhibitory concentration (IC 50) of 1.4 nM. It is applicable in researching multiple ...
T69451	R-130823
	R-130823 is a ighly selective inhibition against mitogen-activated protein kinase p38alpha (IC50=22 nM). The release of tumor necrosis factor-alpha, interleukin-1beta, -6 and -8 was inhibited in lipopolysaccharide-stimul...

Recombinant Proteins

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Expression System：

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Cat No.	Product Name	Species	Expression System
TMPY-03490	IL-22 Protein, Human, Recombinant	Human	E. coli
	IL22 is a member of a group of cytokines called the IL-1 family of IL-1 superfamily (including IL-19, IL-2, IL-24, and IL-26), a class of potent mediators of cellular inflammatory responses. It shares the use of IL-1R2 i...
TMPY-04287	IL-22RA1 Protein, Rat, Recombinant (His)	Rat	HEK293
	IL-22R belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains and is expressed in the colon, liver, lung, pancreas, and kidney. IL-22R also can be expressed in keratinocytes of normal...
TMPY-04286	IL-22RA1 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	IL-22R belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains and is expressed in the colon, liver, lung, pancreas, and kidney. IL-22R also can be expressed in keratinocytes of normal...
TMPY-04087	IL-22RA1 Protein, Canine, Recombinant (His)	Canine	HEK293
	IL-22R belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains and is expressed in the colon, liver, lung, pancreas, and kidney. IL-22R also can be expressed in keratinocytes of normal...
TMPY-04002	IL-22RA1 Protein, Canine, Recombinant (hFc)	Canine	HEK293
	IL-22R belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains and is expressed in the colon, liver, lung, pancreas, and kidney. IL-22R also can be expressed in keratinocytes of normal...
TMPY-04973	IL-22 Protein, Human, Recombinant (His)	Human	Yeast
	IL22 is a member of a group of cytokines called the IL-1 family of IL-1 superfamily (including IL-19, IL-2, IL-24, and IL-26), a class of potent mediators of cellular inflammatory responses. It shares the use of IL-1R2 i...
TMPK-00661	IL-22 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeab...
TMPJ-01340	IL-22 Protein, Mouse, Recombinant (mFc)	Mouse	Human Cells
	Interleukin-22 (IL-22) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acid signal peptide that is cl...
TMPJ-00062	IL-22 Protein, Human, Recombinant (hIgG4 hFc)	Human	Human Cells
	Interleukin-22(IL-22) is a member of a group of the IL-10 family, a class of potent mediators of cellular inflammatory responses. IL-22 is produced by activated DC and T cells. IL-22 and IL-10 receptor chains play a role...
TMPJ-00061	IL-22 Protein, Human, Recombinant (hIgG2 hFc)	Human	Human Cells
	Interleukin-22(IL-22) is a member of a group of the IL-10 family, a class of potent mediators of cellular inflammatory responses. IL-22 is produced by activated DC and T cells. IL-22 and IL-10 receptor chains play a role...
TMPY-04900	IL-22BP Protein, Human, Recombinant (hFc)	Human	HEK293
	Interleukin-22 receptor subunit alpha-2 (IL-22RA2), also known as interleukin-22-binding protein (IL-22BP), is a subunit of the receptor for interleukin 22. IL-22BP belongs to the type II cytokine receptor family and con...
TMPJ-01339	IL-22 Protein, Mouse, Recombinant (E. coli)	Mouse	E. coli
	Interleukin-22 (IL-22) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acid signal peptide that is cl...
TMPK-01194	IL-22 Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	E. coli
	The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeab...
TMPY-01220	IL-22BP Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin-22 receptor subunit alpha-2 (IL-22RA2), also known as interleukin-22-binding protein (IL-22BP), is a subunit of the receptor for interleukin 22. IL-22BP belongs to the type II cytokine receptor family and con...
TMPJ-00119	IL-22RA2 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. I...
TMPY-01324	IL-22BP Protein, Human, Recombinant (His & hFc)	Human	HEK293
	Interleukin-22 receptor subunit alpha-2 (IL-22RA2), also known as interleukin-22-binding protein (IL-22BP), is a subunit of the receptor for interleukin 22. IL-22BP belongs to the type II cytokine receptor family and con...
TMPJ-00076	IL-28B Protein, Human, Recombinant	Human	Human Cells
	Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to pla...
TMPK-01105	IL-22RA1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), ...
TMPK-01071	IL-22RA1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), ...
TMPY-05559	IL-20RB Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors: cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleu...
TMPY-04712	IL-20RB Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors: cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleu...
TMPY-02902	IL-20RB Protein, Rat, Recombinant (His)	Rat	HEK293
	IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors: cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleu...
TMPY-03086	IL-20RB Protein, Rat, Recombinant (hFc)	Rat	HEK293
	IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors: cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleu...
TMPJ-00194	IL-20RB Protein, Human, Recombinant (hFc)	Human	Human Cells
	Interleukin-20 receptor subunit beta（IL20RB） is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytoki...
TMPY-05465	IL-20RB Protein, Mouse, Recombinant (His)	Mouse	HEK293
	IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors: cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleu...
TMPY-04711	IL-20RB Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293
	IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors: cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleu...
TMPK-00405	IL-17RA Protein, Human, Recombinant (aa 33-320, hFc & Avi), Biotinylated	Human	HEK293
	Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known family of receptors. While the expression of IL‑17 is restr...
TMPJ-00077	IL -17C Protein, Human, Recombinant (His & Avi), Biotinylated	Human	Human Cells
	Interleukin 17C (IL 17C) is a 15 20 kDa glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. IL 17C binds to IL 17 RE with high affinity and to IL 17 RA with low affinity. Thes...
TMPJ-00078	IL-17C Protein, Human, Recombinant (His)	Human	Human Cells
	Interleukin 17C (IL 17C) is a 15 20 kDa glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. IL 17C binds to IL 17 RE with high affinity and to IL 17 RA with low affinity. Thes...
TMPJ-01230	IL-17RE Protein, Human, Recombinant (hFc)	Human	Human Cells
	Interleukin 17 Receptor E (IL 17 RE) is an approximately 70 kDa (predicted) transmembrane protein in the family of IL 17 receptors. IL 17 RE is expressed on keratinocytes, mucosal epithelial cells, Th17 cells, and gamma ...
TMPJ-01208	IL-17RE Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Interleukin 17 Receptor E (IL 17 RE) is an approximately 70 kDa (predicted) transmembrane protein in the family of IL 17 receptors. IL 17 RE is expressed on keratinocytes, mucosal epithelial cells, Th17 cells, and gamma ...